COLLEGE FOOTBALL WEEK 4 · BETTING PREVIEW
Illinois vs. Ohio State
Large winning margins need opponent context
Kickoff:
Ohio Stadium · Schedule
Public betting odds
| Team | Spread (price) | Moneyline |
|---|---|---|
| Illinois | +27.5 (-115) | +1600 |
| Ohio State | -27.5 (-105) | -4000 |
Total: 53.5 · Over -115 / Under -105
DraftKings via ESPN · Checked September 24, 2026 at 3:16 PM ET. A source-specific snapshot, not a guaranteed live offer or a placed wager.
What carries into this matchup
Illinois
Illinois beat Southern Illinois Salukis 48–10 on September 19, 2026. The offense finished with 503 total yards, 4-for-10 on third down, 1 turnover. Katin Houser completed 23 of 29 passes for 305 yards, with 2 passing touchdowns and 1 interceptions. Box score · Scoring and play-by-play
Ohio State
Ohio State beat Kent State Golden Flashes 59–3 on September 19, 2026. The offense finished with 527 total yards, 1-for-8 on third down, 2 turnovers. Julian Sayin completed 18 of 22 passes for 241 yards, with 2 passing touchdowns and 0 interceptions. Box score · Scoring and play-by-play
Matchup analysis
Both teams overwhelmed their previous opponents. Illinois’ passing efficiency gives it a route to moving the ball, while Ohio State’s early separation against Kent State shows why the favorite can threaten a large margin. Neither tune-up establishes how reliably those gains translate into a conference game; the underdog’s ability to avoid empty possessions matters more than either raw score.
Availability and news to watch
Ohio State listed right tackle Phillip Daniels and defensive end Zion Grady questionable. Defensive tackle James Smith and running back Legend Bey were cleared after leaving the Kent State game. Ohio State Week 4 availability report
This preview will be updated as the week develops. Current odds are not a betting recommendation. Only wager what you can afford to lose.