NFL / MONDAY NIGHT FOOTBALL / BETTING PREVIEW
Giants to Beat the Rams Tonight: Betting Preview
I think the New York Football Giants are winning tonight. They can control this game the way they did against Dallas. I like them to cover the spread, but I also think they win outright.
New York Giants (1–0) at Los Angeles Rams (0–1). Monday, September 21, 2026 · 8:15 p.m. ET · SoFi Stadium.
DraftKings odds: current spread, moneyline and total could not be verified at publication. See the DraftKings NFL board linked below for live prices.
The Rams are without Myles Garrett, and they gave up one of their best defensive players to acquire him. I thought San Francisco moved the ball pretty well against them in Week 1. I still have questions about the Rams’ defense, particularly the linebacking corps.
Cam Skattebo and Jaxson Dart can make a ton of plays, just as they did against Dallas. I expect Malik Nabers to have a bigger game, too. If New York can keep moving the chains and control the game, this is a real opportunity for the Giants.
There are questions about the Rams’ offense, especially if Puka Nacua is out. He is listed as questionable. Is Matthew Stafford going to be the same guy he was last year? He did not look like that to me in Week 1. We will see whether he looks like that in Week 2.
That could end up killing this pick, because I think the Giants’ cornerbacks are really bad. If Stafford gets comfortable, that matchup is a problem. The Giants need to dial up blitzes and get to him.
If New York can create that pressure and keep making plays on offense, I think this is going to be a massive game for the Giants. My prediction: Giants cover and win outright.